Retinol unsafe during pregnancy

The importance of avoiding retinol in pregnancy

Pregnancy brings with it a myriad of changes – both in your body and your life. As an expecting mother, you are committed to ensuring the health and happiness of your growing baby. Your choices, especially concerning skincare, can have far-reaching effects during this crucial period.

Here we will unpack the reasons why retinol, a popular skincare ingredient, should be avoided during pregnancy.

Our aim is to provide you with comprehensive information backed by studies and statistics, empowering you to make informed decisions that keep both you and your baby safe.

The power of retinol

Retinol, often hailed as a beauty miracle worker, is a derivative of vitamin A that has gained a prominent spot in many skincare routines. Celebrated for its remarkable ability to minimise fine lines, wrinkles, and uneven skin tone, retinol has become a trusted ally for those seeking youthful skin. However, its potency and transformative effects come with certain concerns, especially for expectant mothers.

Understanding the risks

The allure of retinol is undeniable, but research suggests that it may carry potential risks during pregnancy.

It's important to note that retinol, when taken in high doses, can be linked to birth defects and developmental problems in the foetus. A study published in the Journal of the American Academy of Dermatology (1) emphasised the need for caution, as excessive vitamin A intake during pregnancy has been associated with an increased risk of congenital malformations. These risks are particularly pronounced during the first trimester, when foetal development is at a critical stage.

Vitamin A unsafe during pregnancy

The Power of Statistics 

Let's delve into the statistics that offer a clear view of the potential risks associated with retinol use during pregnancy:

  1. Congenital Malformations: The National Birth Defects Prevention Study (2) conducted extensive research on the effects of high-dose vitamin A supplements during early pregnancy. The study revealed a significant association between maternal use of such supplements and specific birth defects.
  1. Neural Tube Defects: Neural tube defects, serious conditions that affect a baby's brain, spine, or spinal cord, are of particular concern. A study published in the British Journal of Clinical Pharmacology (3) highlighted the increased risk of neural tube defects due to excessive vitamin A exposure, including from retinol.
  1. Oral Isotretinoin: While not directly related to topical retinol, it's noteworthy that oral isotretinoin, a medication derived from retinoids and used to treat severe acne, is notorious for causing severe birth defects. The FDA (4) has mandated strict warnings and restrictions on isotretinoin due to its potential to harm the developing foetus.
  1. Topical Retinoids: Even though topical retinoids are generally considered less risky than their oral counterparts, the American College of Obstetricians and Gynaecologists (5) advises pregnant women to steer clear of them due to the limited research available on their safety during pregnancy.

A gentle approach to skincare

As an expecting mother, your priority is the well-being of your baby. While the allure of retinol's transformative effects might be tempting, there are alternative skincare ingredients that are safe and effective for pregnancy. Here are some recommendations:

  1. Hyaluronic Acid Serum: This hydrating ingredient is your skin's best friend during pregnancy. It helps maintain moisture, promoting a plump and youthful complexion.
  1. Vitamin C Serum: Renowned for its antioxidant properties, vitamin C is safe for pregnancy and can help brighten the skin while supporting collagen production.
  1. Glycolic Acid: Derived from sugarcane, glycolic acid is an excellent exfoliant that can improve skin texture and tone, without the risks associated with retinol.
  1. Natural Oils: Embrace the power of nature with ingredients like rosehip oil and argan oil. These oils are rich in antioxidants and fatty acids, providing nourishment to your skin.

Embrace your pregnancy journey armed with all the facts!

Your pregnancy journey is a time of transformation, and every decision you make contributes to the health and happiness of both you and your baby. While retinol might promise a youthful appearance, the potential risks it carries during pregnancy cannot be overlooked. By embracing safer alternatives, you're prioritising the safety of your little one while still taking care of your skin's needs. Always consult with your healthcare provider before commencing any new skincare regime.


Steer clear of retinol and vitamin A during pregnancy 

1: Reference for study on vitamin A intake and congenital malformations: Journal of the American Academy of Dermatology, 2007; 57(3): 401-414.

2: National Birth Defects Prevention Study:

3: Reference for research on vitamin A exposure and neural tube defects: British Journal of Clinical Pharmacology, 2012; 74(2): 369-375.

4: FDA information on isotretinoin:

5: American College of Obstetricians and Gynaecologists recommendations:

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